Reiji Yoshimura Selected Research

Brain-Derived Neurotrophic Factor (BDNF)

4/2022	Volume of Amygdala Subregions and Plasma Levels of Brain-Derived Neurotrophic Factor and Cortisol in Patients with s/s Genotype of Serotonin Transporter Gene Polymorphism of First-Episode and Drug-Naive Major Depressive Disorder: An Exploratory Study.
1/2022	Associations of Serum Cytokines, Growth Factors, and High-Sensitivity C-Reactive Protein Levels in Patients with Major Depression with and without Type 2 Diabetes Mellitus: An Explanatory Investigation.
1/2021	Associations Between the Kynurenine Pathway, Proinflammatory Cytokines, and Brain-Derived Neurotrophic Factor in Hospitalized Patients With Chronic Schizophrenia: A Preliminary Study.
1/2018	The Impact of Aging, Psychotic Symptoms, Medication, and Brain-Derived Neurotrophic Factor on Cognitive Impairment in Japanese Chronic Schizophrenia Patients.
3/2017	Blood Biomarkers Predict the Cognitive Effects of Aripiprazole in Patients with Acute Schizophrenia.
1/2017	Relationships between serum brain-derived neurotrophic factor, plasma catecholamine metabolites, cytokines, cognitive function and clinical symptoms in Japanese patients with chronic schizophrenia treated with atypical antipsychotic monotherapy.
1/2017	Brain-Derived Neurotrophic Factor and Major Depressive Disorder: Evidence from Meta-Analyses.
1/2016	Serum levels of brain-derived neurotrophic factor (BDNF), proBDNF and plasma 3-methoxy-4-hydroxyphenylglycol levels in chronic schizophrenia.
8/2015	Relationship between a BDNF gene polymorphism and the brain volume in treatment-naive patients with major depressive disorder: A VBM analysis of brain MRI.
4/2014	Duloxetine, a Selective Noradrenaline Reuptake Inhibitor, Increased Plasma Levels of 3-Methoxy-4-hydroxyphenylglycol but Not Homovanillic Acid in Patients with Major Depressive Disorder.

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Reiji Yoshimura Research Topics

Disease

48	Major Depressive Disorder (Major Depressive Disorders) 04/2022 - 01/2002
44	Schizophrenia (Dementia Praecox) 01/2021 - 03/2003
8	Bipolar Disorder (Manic Depressive Psychosis) 01/2021 - 10/2006
7	Psychotic Disorders (Schizoaffective Disorder) 01/2018 - 06/2000
6	Mental Disorders (Mental Disorder) 01/2021 - 03/2010
5	Mania (Manias) 01/2022 - 10/2006
5	Mood Disorders (Mood Disorder) 01/2020 - 07/2010
5	Treatment-Resistant Depressive Disorder 04/2012 - 07/2008
5	Depressive Disorder (Melancholia) 11/2010 - 01/2007
4	Cognitive Dysfunction 01/2018 - 12/2009
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 03/2013 - 12/2008
4	Anxiety Disorders (Anxiety Disorder) 08/2010 - 09/2007
3	COVID-19 10/2021 - 01/2020
3	Atrophy 10/2019 - 11/2010
3	Hyperprolactinemia 02/2019 - 03/2012
2	Burning Mouth Syndrome (Syndrome, Burning Mouth) 01/2021 - 06/2008
2	Body Weight (Weight, Body) 12/2020 - 11/2020
2	Psychomotor Agitation (Akathisia) 12/2020 - 02/2019
2	Substance-Related Disorders (Drug Abuse) 01/2020 - 01/2014
2	Cerebral Cortical Thinning 01/2018 - 09/2015
2	Meige Syndrome 09/2016 - 01/2011
2	Tobacco Use Disorder (Nicotine Dependence) 04/2012 - 04/2010
2	Occupational Stress 04/2011 - 04/2008
2	Alcoholism (Alcohol Abuse) 07/2009 - 01/2009
1	Type 2 Diabetes Mellitus (MODY) 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2021
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 07/2021
1	Parkinson Disease (Parkinson's Disease) 06/2021
1	Fever (Fevers) 05/2021
1	Abdominal Pain (Pain, Abdominal) 05/2021
1	Familial Mediterranean Fever (Periodic Disease) 05/2021
1	Tinnitus 01/2021
1	Tardive Dyskinesia 01/2021
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2021
1	Constipation 12/2020
1	Sleepiness 12/2020
1	Weight Gain 12/2020

Drug/Important Bio-Agent (IBA)

38	Brain-Derived Neurotrophic Factor (BDNF)IBA 04/2022 - 06/2006
21	Pharmaceutical PreparationsIBA 04/2022 - 01/2003
19	Antipsychotic Agents (Antipsychotics)IBA 04/2020 - 10/2006
16	Risperidone (Risperdal Consta)FDA LinkGeneric 02/2019 - 03/2003
16	CatecholaminesIBA 01/2019 - 06/2006
13	Antidepressive Agents (Antidepressants)IBA 03/2022 - 01/2007
13	MethoxyhydroxyphenylglycolIBA 03/2017 - 03/2005
12	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 06/2014 - 01/2003
9	Homovanillic AcidIBA 03/2017 - 03/2003
8	Aripiprazole (Abilify)FDA Link 03/2017 - 01/2009
8	Fluvoxamine (Luvox)FDA LinkGeneric 01/2017 - 01/2002
7	Interleukin-6 (Interleukin 6)IBA 01/2022 - 06/2009
7	Olanzapine (Zyprexa)FDA Link 12/2020 - 01/2007
7	Biomarkers (Surrogate Marker)IBA 03/2017 - 04/2008
7	Paroxetine (Paxil)FDA LinkGeneric 06/2014 - 01/2003
6	CytokinesIBA 01/2022 - 04/2008
6	Serotonin (5 Hydroxytryptamine)IBA 12/2012 - 09/2007
5	Hydrocortisone (Cortisol)FDA LinkGeneric 04/2022 - 09/2015
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2022 - 11/2009
4	VortioxetineIBA 06/2021 - 01/2020
4	Serotonin and Noradrenaline Reuptake InhibitorsIBA 04/2012 - 01/2007
4	Caffeine (No Doz)FDA LinkGeneric 12/2011 - 01/2002
4	gamma-Aminobutyric Acid (GABA)IBA 12/2010 - 07/2009
3	InterleukinsIBA 01/2022 - 09/2013
3	Valproic Acid (Depakote)FDA LinkGeneric 07/2021 - 03/2013
3	LithiumIBA 11/2020 - 06/2014
3	blonanserinIBA 04/2020 - 01/2014
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 04/2014 - 09/2007
3	Sertraline (Zoloft)FDA LinkGeneric 12/2012 - 12/2008
2	Insulin-Like PeptidesIBA 01/2022 - 01/2021
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 10/2019
2	ORALIT (ORS)IBA 10/2021 - 01/2021
2	Escitalopram FDA Link 05/2021 - 01/2021
2	Clozapine (Clozaril)FDA LinkGeneric 01/2021 - 10/2016
2	Glutamic Acid (Glutamate)FDA Link 01/2021 - 01/2012
2	Carbamazepine (Tegretol)FDA LinkGeneric 11/2020 - 06/2000
2	Paliperidone Palmitate FDA Link 02/2019 - 09/2016
2	Dopamine (Intropin)FDA LinkGeneric 01/2019 - 10/2008
2	Duloxetine Hydrochloride (Cymbalta)FDA Link 01/2015 - 04/2014
2	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 01/2015 - 01/2014
2	SteroidsIBA 01/2012 - 09/2006
2	serotonin 6 receptorIBA 08/2010 - 07/2010
2	Nerve Growth Factors (Neurotrophins)IBA 01/2009 - 01/2009
2	CotinineIBA 03/2005 - 01/2002
1	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 04/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022
1	C-Reactive ProteinIBA 01/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	Interleukin-8 (Interleukin 8)IBA 01/2022
1	Interleukin-10 (Interleukin 10)IBA 01/2022
1	Colchicine FDA LinkGeneric 05/2021
1	Urea (Carbamide)FDA LinkGeneric 01/2021
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2021
1	KynurenineIBA 01/2021
1	Psychotropic Drugs (Psychoactive Drugs)IBA 01/2021
1	Tryptophan (L-Tryptophan)FDA Link 01/2021
1	LDL CholesterolIBA 12/2020
1	CholesterolIBA 12/2020
1	Triglycerides (Triacylglycerol)IBA 12/2020
1	Lurasidone Hydrochloride FDA Link 12/2020
1	ProlactinIBA 12/2020

Therapy/Procedure

5	Polypharmacy 01/2021 - 06/2012
4	Therapeutics 04/2014 - 10/2006